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Jun 10 2016

After the Piroxicam storm

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I have been hoping to get to the beginning of our story and the start of Pofi’s Tripawd journey, but after our all clear lymph node cytology, we had a stormy night.  I gave Pofi his first dose of Piroxicam in the morning as the anti inflammatory part of our evolving Metronomic chemo approach.  And we were to start alternating the Cyclophosphamide with Palladia today.  But our sage Oncologist had suggested staggering the new meds so I could be certain if which, if any, caused any unwanted effect.

Well, Tuesday night, Pofi seemed a little hesitant about food and treats, but ate pretty easily.  I noticed soon after, however, that he was uncharacteristically “windy” and it was pretty unpleasant.  I gave the chemo anyhow, which probably was not advisable.  About 1:30 AM, we were awoken by a retching, restless dog.  He wasn’t really bringing anything up initially, but he was trying awfully hard.  And then for the next few hours, I let him out a few times and for multiple bowel movements, poor lad.  And he did finally retch up some liquid, too.  Since we never have stomach upset, I did not have Pepcid AC on hand.  Spoke to the Oncology department in the morning and we decided on a one to two day medication holiday for him except for some Pepcid to help settle his gurgling tummy.  He also was still sort of clearing his throat on Tuesday morning, but it lessened pretty quickly.  I can only think the combination of intubation GA the day before for CT and then all that retching really irritated his throat.  This wasn’t really coughing- didn’t come from chest at all, but of course, PARANOID so thank you fellow Tripawd members for talking me off a ledge in the chat room.  You know who you are!  🙂

I did add one Mirtazapine on Tuesday evening along with the newly procured Pepcid AC to make certain we got past the resulting inappetance (breakfast was a big “No thanks” in the morning).  And we seem to be back on track.  Plan now is to pick up the Palladia this weekend and start it Monday.  For now, we will use Rimadyl as the anti inflammatory component, but perhaps I’ll try Piroxicam, which is less toxic to the liver, in the future with Pepcid…if I am brave enough!

For now, a few glamour shots of my boy and his sister, Mia.


Pofi profile

Mia enjoying her first dip in the Pacific in Santa Barbara, Sept 2013

Mia enjoying her first dip in the Pacific in Santa Barbara, Sept 2013

Pofi happily embracing the ocean for the first time, Sept 2013

Pofi happily embracing the ocean for the first time, Sept 2013



6 responses so far

6 Responses to “After the Piroxicam storm”

  1.   Michelleon 10 Jun 2016 at 8:37 pm

    Sounds good. I was thinking did you start with the Palladia first? If so that could be causing the GI upset too because that is one of the side affects of that drug. Just a thought

    Michelle & Angel Sassy


    •   hesteron 10 Jun 2016 at 8:43 pm

      Thanks, Michelle – will be stocking Pepcid AC from now on. But no, we haven’t started the Palladia – so definitely the Piroxicam. The bad gas started before I gave him the Cyclophosphamide that night and he has shown no sensitivity to that. But it probably was too much on top of already having some gastric upset. I think it turned into a double whammy…. He had the Cyclophosphamide again last night and a Pepcid AC in advance to help make sure it was not and issue for him. He is feeling much better – brought me a toy to play tug with just a few minutes ago!!! <3


  2.   benny55on 10 Jun 2016 at 10:25 pm

    Ugh….and YAY! Sorry you had this bump in the road, but glad everything has been resolved! Kudos to you for doing such a good job of staying on top of things.

    I know it was unsettling and scary for a bit, but I think you’re spot on about it being a double whammy.

    And they are glamour shots indeed!! BEAUTIFUL, BEAUTIFUL PHOTOS OF MIA AND POFI! Two very good looking dogs!

    Okay Pofi, no more tummy upsets and stinky toots! Although, etween the teomof us, we know it was your humans doing the stinky toots and “blaming the dog”! 🙂

    Cheering like crazy for you Pofi! Hugs to all your pack!

    Sally and Alumni Happy Hannah and Merry Myrtle and Frankie too!


    •   hesteron 10 Jun 2016 at 10:41 pm

      I agree, Sally and crew, no more tummy drama stunts!! Seriously, though, he is never a smelly dog – totally unusual!!!


  3.   jerryon 19 Jun 2016 at 3:32 pm

    Hester, I’ve been so distracted lately with working 2 jobs I haven’t had a chance to peruse the blogs. I’m so sorry about this scare (I would have FREAKED) but super happy to know things are going better for Pofi. And he is most definitely a glamorous pup (as is Mia!). Kudos to you for handing everything so well, you’re a great pack leader.


  4.   hesteron 19 Jun 2016 at 5:44 pm

    Thanks, Jerry. It was a downer after the good news on lymph nodes for sure! Very nerve wracking. But we are staying the course and all is well for now!


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